The primary purpose of this study is to compare the efficacy of adapalene Official Title: A Comparative Study of Adapalene Gel % Versus Tretinoin %. Retin-A (tretinoin) Cream and Gel and Differin (adapalene) are retinoids (a form of vitamin A) used for the topical treatment of acne vulgaris. Side effects of Retin-A and Differin that are similar include skin warmth, stinging, tingling, irritation, redness, dryness, itching. Official Title: Split-face Tolerability Comparison Between Epiduo® (Adapalene and Benzoyl Peroxide) Gel %/% Versus Retin-A Micro® (Tretinoin Gel). Active Comparator: adapalene adapalene. Warning You have reached the maximum number of saved studies It exhibits selective affinity for nuclear retinoic acid receptors and does not bind to cytosolic retinoic acid binding proteins. The safety and scientific validity of this study link the responsibility of the study sponsor and investigators. Many people worry that the use of retinoids will make their skin more sensitive in the sun. Everyone has a different skin type and acne can have multiple causes - a treatment that works perfectly for one person might be less effective or cause greater irritation in another. Number of tfetinoin who improved in Overall Integrated Assessment of Photodamage from baseline to week In head-to-head trials, it has been found to be similarly effective to Differin, and since azelaic acid is less prone to causing dryness than adapalene, Skinoren is an excellent alternative. Please refer to this study by its ClinicalTrials. Since Asian skin types tend to be more highly pigmented than those of white people of European descent, many Asians share the predisposition toward postinflammatory article source seen in Africans, African-Americans and other dark-skinned peoples. Please refer to this study by its ClinicalTrials. Outcome Measures. Retinoid vs. Hold on to your tdetinoin — this is untrue. Results First Posted : February 24, Learn more here Asian skin types tend to be more highly pigmented than those of white people of European descent, many Asians share the adpaalene toward postinflammatory hyperpigmentation seen in Africans, African-Americans and other dark-skinned peoples. Learn acne types, causes and best ways to deal. Because of this, it isn't always the best option. This is beneficial because one of the natural signs of getting older is thinning of adapalene vs tretinoin skin. Dalacin-T is a lotion or solution containing the equivalent of 10mg clindamycin in every 1ml. Retinol: Common ingredient found in food like meat and poultry, and in certain skin-care products. You May Also Like. Read this next. Outcome Measures. What are adapalene and tretinoin? Here's how they differ:. Ultimately, the treatment you should use for your acne will depend not only on the severity and nature of your symptoms but also on how you react to different treatments. Want to learn even more about retinoids and the important role they play in treating acne? Typical side effects include dryness, tightness, peeling, and redness — especially when first starting out.